The Material Salvage and Reuse Innovation (MSRI) Hub is a joint venture between the MSU Center for Community and Economic Development’s Domicology Team, and the Michigan Department of Environment, Great Lakes, and Energy (EGLE). For the past 5 years, the MSU Domicology team has worked collaboratively with a wide array of stakeholders to develop innovative policies and practices that allow for communities to leverage positive social, economic, and environmental impacts by harnessing the value of materials present in abandoned and blighted structures. By partnering with EGLE to form the MSRI Hub, the Domicology team has been able to expand its scope to provide direct technical assistance and support to businesses and community organizations across the state involved in the deconstruction, salvaging, recovery, recycling, and upcycling of structural materials and building components. This partnership has also enabled the MSRI hub to conduct groundbreaking research in utilizing salvaged and reclaimed wood to create new mass timber building components; an innovation that could have massive implications for creating viable regional economies around a currently underutilized waste stream.